Ship on Dry Ice
LinkLight™ U2-OS CCKBR / β-arrestin Cell Line is a stable monoclonal cell line in U2-OS cells, targeting Human CCKBR pathway via b-arrestin. The proprietary LinkLight™ technology uses a standard Luciferase Assay as the detection method.
CCKBR acts as a receptor for gastrin and cholecystokinin (CCK), and has a high affinity for both sulfated and unsulfated CCK analogs and is found principally in the central nervous system and the gastrointestinal tract. CCKBR with a mutation variant in transcription has been reported in cells from colorectal and pancreatic tumors.
Host Cell Lines:
Standard Luciferase Assay System for mammalian cells should be followed according to Assay kit manufacturer protocol.