Ship on Dry Ice
LinkLight™ U2-OS CCKAR / β-arrestin Cell Line is a stable monoclonal cell line in U2-OS cells, targeting Human CCKAR pathway via b-arrestin. The proprietary LinkLight™ technology uses a standard Luciferase Assay as the detection method.
CCKAR acts as receptor that binds non-sulfated members of the cholecystokinin (CCK) family of peptide hormones. CCKAR mediates pancreatic enzyme secretion and smooth muscle contraction of the gallbladder and stomach, and regulates satiety and the release of beta-endorphin and dopamine in the central and peripheral nervous system.
Host Cell Lines:
Standard Luciferase Assay System for mammalian cells should be followed according to Assay kit manufacturer protocol.