Ship on Dry Ice
LinkLight™ U2-OS BDKRB1 / β-arrestin Cell Line is a stable monoclonal cell line in U2-OS cells, targeting Human BDKRB1 pathway via b-arrestin. The proprietary LinkLight™ technology uses a standard Luciferase Assay as the detection method.
BDKRB1 acts as a receptor for bradykinin. The 9 aa bradykinin peptide is generated in conditions such as inflammation, trauma, burns, shock, and allergy. BDKRB1 acts as a receptor which binds to bradykinin and mediate responses to these conditions. Receptor binding leads to cytosolic calcium ion concentration increase, resulting in acute/chronic inflammatory responses.
Host Cell Lines:
Standard Luciferase Assay System for mammalian cells should be followed according to Assay kit manufacturer protocol.