M5, Muscarinic acetylcholine receptor M5, CHRM5
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LinkLight™ HEK293 CHRM5 GPCR/14-3-3 Cell Line is a stable monoclonal cell line in HEK293 cells, targeting Human CHRM5 pathway via 14-3-3. The proprietary LinkLight™ technology uses a standard Luciferase Assay as the detection method.
CHRM5 is a member of G protein-coupled receptor superfamily. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The clinical implications of this receptor are unknown; however, stimulation of this receptor is known to increase cyclic AMP levels.
Host Cell Lines:
Standard Luciferase Assay System for mammalian cells should be followed according to Assay kit manufacturer protocol.