Tel: 800-943-6396 Fax: 888-253-6691 Email: info@bonopusbio.com

Contact us:

Bon Opus Biosciences LLC 86 Summit Ave. Suite LL300B Summit NJ 07901 USA Tel: 800-943-6396 Fax: 888-253-6691

Emails:

General Information: info@bonopusbio.com Ordering: orders@bonopusbio.com

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BC050063
2 Vials
$17,000.00
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Cat No.: 
BC050063

LinkLight™ HEK293 ADRB2 GPCR/14-3-3 Cell Line

Collection: 
Product Type: 
ALTnames: 
β2AR, Beta-2 adrenergic receptor, Beta-2 adrenoreceptor, ADRB2, ADRB2R, B2AR
Packaging: 
Ship on Dry Ice
Storage: 
Liquid Nitrogen
Description: 
LinkLight™ HEK293 ADRB2 GPCR/14-3-3 Cell Line is a stable monoclonal cell line in HEK293 cells, targeting Human ADRB2 pathway via 14-3-3. The proprietary LinkLight™ technology uses a standard Luciferase Assay as the detection method.
Background: 
ADRB2 is a member of the G protein-coupled receptor superfamily. ADRB2 is directly associated with the class C L-type calcium channel Ca(V)1.2. This receptor-channel complex also contains a G protein, an adenylyl cyclase, cAMP-dependent kinase, and the counterbalancing phosphatase, PP2A. This gene is intronless, and different polymorphic forms, point mutations, and/or downregulation of this gene are associated with nocturnal asthma, obesity and type 2 diabetes.
8001-S
Target Protein: 
ADRB2
Target Species: 
Human
Accession Number: 
P07550
Host Cell Lines: 
HEK293
Assay Protocol: 
Standard Luciferase Assay System for mammalian cells should be followed according to Assay kit manufacturer protocol.