CAR1, CAR, MB67, Nuclear receptor subfamily 1 group I member 3, Constitutive active response, Constitutive androstane receptor, MB67
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HepG2 CAR1 / 2B6-Luciferase Cell Line is a Transiently Transfected cell line in HepG2 cells, targeting the CAR1 pathway via 2B6-Luciferase Assay Cells, and uses a standard Luciferase Assay as the detection method.
CAR1, also known as Constitutive Androstane Receptor, binds and transactivates the retinoic acid response that controls both retinoic acid receptor beta 2 and alcohol dehydrogenase 3 gene expression. CAR1 also transactivates phenobarbital response of human CYP2B6 gene and the CYP3A4 xenobiotic response element.
Host Cell Lines:
Standard Luciferase Assay System for mammalian cells should be followed according to Assay kit manufacturer protocol.